![]() ![]() This indicates that the genetic etiology of hedonic and eudaimonic well-being is substantially shared, with divergent (environmental) factors contributing to their phenotypic divergence. Joint analyses revealed a moderate phenotypic correlation ( r = 0.53) and a high genetic correlation ( r g = 0.78) between eudaimonic and hedonic well-being. We identified the first two genome-wide significant independent loci for eudaimonic well-being and six independent loci for hedonic well-being. ![]() Hence, we conducted the first genome-wide association studies (GWAS) of eudaimonic well-being ( N = ~108 K) and linked it to a GWAS of hedonic well-being ( N = ~222 K). To shed light on the relation between the two, large-scale available molecular genetic data were leveraged to gain more insight into the genetic architecture of the overlap between hedonic and eudaimonic well-being. Whether hedonism or eudaimonia are two distinguishable forms of well-being is a topic of ongoing debate. ![]()
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